The defibrase group showed noticeable effects in reducing hageman factor I, platelet aggregation second phase ( PAG max), hematocrit, and thrombus index Q ( P < 0.01). No adverse reactions were found. 降纤酶有非常显著的降低凝血因子I、血小板最大聚集率、血细胞比容和血栓指数Q值的作用(P<0.01),且无明显不良反应。